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Cardiology

Your essential source for clinically relevant perspectives – from physician opinion leaders – on the most important research and guidelines in cardiovascular medicine

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Beta-Blockers for Noncardiac Surgery: A Shift in Balance?

  • Summary and Comment
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Results from the POISE trial suggest that the risks of initiating beta-blockers may outweigh the benefits.

Troponin Levels and Prognosis in Patients with Acute Heart Failure

  • Summary and Comment
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In an observational study, elevations in cardiac troponin predicted poor outcome — but does routine testing substantially affect treatment decisions?

Cardiovascular Risk Prediction: Beyond the Established Risk Factors

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The inclusion of four biomarkers may improve risk stratification — at least among older men.

Delayed Presentation for ST-Segment-Elevation MI: Which Patients Are at Greatest Risk?

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An analysis of nationwide data profiles the most vulnerable; whether targeted interventions can improve outcomes remains to be seen.

Early Repolarization in Survivors of Idiopathic Ventricular Fibrillation

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In a case-control study, nearly one third of patients who survived sudden cardiac arrest had marked early repolarization.

Surgical Sympathetic Denervation for Catecholaminergic Polymorphic Ventricular Tachycardia

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Sometimes the best treatment is not the newest.

Can Adjustment of Clopidogrel Dosing Reduce Ischemic Events After Stent Implantation?

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In a small but promising trial, adjusting the loading dose according to platelet reactivity improved clinical outcomes.

In Stent Recipients Taking Clopidogrel, High Platelet Reactivity Predicts Ischemic Events

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In a prospective observational study, results of a point-of-care platelet-function assay correlated well with thrombotic risk after DES implantation.

A New Drug-Eluting Stent on the Horizon

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Everolimus-eluting stents perform well in a comparison with paclitaxel-eluting stents, setting the stage for FDA approval and — more important — long-term outcome studies.

Genetic Causes of Cardiac Hypertrophy

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An analysis of affected children identifies mutations in several genes previously implicated in adult-onset disease.

Are High-Dose Tirofiban and Drug-Eluting Stents Best for STEMI?

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Results of a randomized study favor SES over BMS and show a high-dose bolus of tirofiban to be as good as abciximab.

Browse our complete Cardiology archive >>

Editor's Picks from across Journal Watch

Caution Urged When Combining Lopinavir/Ritonavir and Rosuvastatin

  • HIV/AIDS
  • Summary and Comment
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In a pharmacokinetic study involving 20 healthy volunteers, coadministration of lopinavir/ritonavir and rosuvastatin significantly increased rosuvastatin levels yet attenuated the LDL-lowering effect of the drug; one study participant experienced a grade 4 elevation in creatinine phosphokinase levels.

Oral Bisphosphonates Do Not Increase Risk for Atrial Fibrillation and Flutter

  • General Medicine
  • Summary and Comment
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A previous finding of increased risk for atrial fibrillation and flutter after IV bisphosphonate was not observed in orally treated patients.

Length of Hospital Stay and Mortality in Patients with Pulmonary Embolism

  • Hospital Medicine
  • Summary and Comment
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Early discharge of patients with PE was associated with higher 30-day postdischarge mortality.

Heart Failure and Perioperative Mortality

  • General Medicine
  • Summary and Comment
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In two studies, heart failure conferred a higher mortality risk after noncardiac surgery.

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Journal Watch Cardiology summarizes important medical journal articles about a wide variety of cardiovascular subjects including angina, atrial fibrillation, coronary artery disease, heart failure, hypertension, myocardial infarction, stents, stroke and ventricular fibrillation.

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Editor-in-Chief >

Harlan Krumholz, MD, SM
Harlan M. Krumholz, MD, SM
Harold H. Hines, Jr., Professor of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine

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