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Cardiology
Your essential source for clinically relevant perspectives – from physician opinion leaders – on the most important research and guidelines in cardiovascular medicine

Beta-Blockers for Noncardiac Surgery: A Shift in Balance?
- Summary and Comment
- Free
Results from the POISE trial suggest that the risks of initiating beta-blockers may outweigh the benefits.
- By Harlan M. Krumholz, MD, SM
- May 14, 2008
- Covering Lancet 2008 May 13
Troponin Levels and Prognosis in Patients with Acute Heart Failure
- Summary and Comment
- Free
In an observational study, elevations in cardiac troponin predicted poor outcome — but does routine testing substantially affect treatment decisions?
- By Harlan M. Krumholz, MD, SM
- May 14, 2008
- Covering N Engl J Med 2008 May 15
Cardiovascular Risk Prediction: Beyond the Established Risk Factors
- Summary and Comment
- Subscription required
The inclusion of four biomarkers may improve risk stratification — at least among older men.
- By Beat J. Meyer, MD
- May 14, 2008
- Covering N Engl J Med 2008 May 15
Delayed Presentation for ST-Segment-Elevation MI: Which Patients Are at Greatest Risk?
- Summary and Comment
- Subscription required
An analysis of nationwide data profiles the most vulnerable; whether targeted interventions can improve outcomes remains to be seen.
- By Frederick A. Masoudi, MD, MSPH
- May 14, 2008
- Covering Arch Intern Med 2008 May 12
Early Repolarization in Survivors of Idiopathic Ventricular Fibrillation
- Summary and Comment
- Subscription required
In a case-control study, nearly one third of patients who survived sudden cardiac arrest had marked early repolarization.
- By Mark S. Link, MD
- May 14, 2008
- Covering N Engl J Med 2008 May 8
Surgical Sympathetic Denervation for Catecholaminergic Polymorphic Ventricular Tachycardia
- Summary and Comment
- Subscription required
Sometimes the best treatment is not the newest.
- By Mark S. Link, MD
- May 14, 2008
- Covering N Engl J Med 2008 May 8
Can Adjustment of Clopidogrel Dosing Reduce Ischemic Events After Stent Implantation?
- Summary and Comment
- Subscription required
In a small but promising trial, adjusting the loading dose according to platelet reactivity improved clinical outcomes.
- By Howard C. Herrmann, MD
- May 14, 2008
- Covering J Am Coll Cardiol 2008 Apr 8
In Stent Recipients Taking Clopidogrel, High Platelet Reactivity Predicts Ischemic Events
- Summary and Comment
- Subscription required
In a prospective observational study, results of a point-of-care platelet-function assay correlated well with thrombotic risk after DES implantation.
- By Beat J. Meyer, MD
- May 14, 2008
- Covering Eur Heart J 2008 Apr
A New Drug-Eluting Stent on the Horizon
- Summary and Comment
- Subscription required
Everolimus-eluting stents perform well in a comparison with paclitaxel-eluting stents, setting the stage for FDA approval and — more important — long-term outcome studies.
- By Howard C. Herrmann, MD
- May 7, 2008
- Covering JAMA 2008 Apr 23
Genetic Causes of Cardiac Hypertrophy
- Summary and Comment
- Subscription required
An analysis of affected children identifies mutations in several genes previously implicated in adult-onset disease.
- By Harlan M. Krumholz, MD, SM
- May 7, 2008
- Covering N Engl J Med 2008 May 1
Are High-Dose Tirofiban and Drug-Eluting Stents Best for STEMI?
- Summary and Comment
- Subscription required
Results of a randomized study favor SES over BMS and show a high-dose bolus of tirofiban to be as good as abciximab.
- By Howard C. Herrmann, MD
- April 30, 2008
- Covering JAMA 2008 Apr 16
Editor's Picks from across Journal Watch
Caution Urged When Combining Lopinavir/Ritonavir and Rosuvastatin
- HIV/AIDS
- Summary and Comment
- Subscription required
In a pharmacokinetic study involving 20 healthy volunteers, coadministration of lopinavir/ritonavir and rosuvastatin significantly increased rosuvastatin levels yet attenuated the LDL-lowering effect of the drug; one study participant experienced a grade 4 elevation in creatinine phosphokinase levels.
- By Keith Henry, MD
- April 28, 2008
- Covering J Acquir Immune Defic Syndr 2008 Apr 15
Oral Bisphosphonates Do Not Increase Risk for Atrial Fibrillation and Flutter
- General Medicine
- Summary and Comment
- Subscription required
A previous finding of increased risk for atrial fibrillation and flutter after IV bisphosphonate was not observed in orally treated patients.
- By Paul S. Mueller, MD, MPH, FACP
- April 8, 2008
- Covering BMJ 2008 Mar 11
Length of Hospital Stay and Mortality in Patients with Pulmonary Embolism
- Hospital Medicine
- Summary and Comment
- Subscription required
Early discharge of patients with PE was associated with higher 30-day postdischarge mortality.
- By Neil Winawer, MD
- April 18, 2008
- Covering Arch Intern Med 2008 Apr 14
Heart Failure and Perioperative Mortality
- General Medicine
- Summary and Comment
- Subscription required
In two studies, heart failure conferred a higher mortality risk after noncardiac surgery.
- By Allan S. Brett, MD
- April 24, 2008
- Covering Anesthesiology 2008 Apr
Journal Watch Cardiology summarizes important medical journal articles about a wide variety of cardiovascular subjects including angina, atrial fibrillation, coronary artery disease, heart failure, hypertension, myocardial infarction, stents, stroke and ventricular fibrillation.
