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Search for Coronary Artery Disease in Cardiology
Physician-authored summaries on the latest research on coronary artery disease, editorials on coronary artery disease, and perspectives on coronary artery disease - drawn from the top medical journals.
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You searched for: coronary artery disease in Cardiology
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Stenting or Medical Therapy for Stable CAD: A Game Changer?
- March 21, 2012
- Frederick A. Masoudi, MD, MSPH, FACC, FAHA
- Cardiology
A new meta-analysis convincingly supports optimal medical therapy as an initial approach.
CME Exam- Reviewing:
- Stergiopoulos K and Brown DL., Arch Intern Med 2012 Feb 27; 172:312.
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CT Angiography: Effect of Pretest Probability and Calcium Score on Predictive Values
- February 29, 2012
- Kirsten E. Fleischmann, MD, MPH
- Cardiology
The inclusion of two widely known risk factors in predictive analysis narrows the range of situations for which CTA is an appropriate diagnostic tool.- Reviewing:
- Arbab-Zadeh A et al., J Am Coll Cardiol 2012 Jan 24; 59:379. Nissen SE., J Am Coll Cardiol 2012 Jan 24; 59:388.
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Combining FAME and SYNTAX in a Functional Score Improves Risk Assessment
- November 2, 2011
- Howard C. Herrmann, MD
- Cardiology
Using ischemia-producing lesions only in the SYNTAX score reduces the number of highest-risk patients and improves prediction of adverse events in patients with multivessel CAD.
CME Exam- Reviewing:
- Nam C-W et al., J Am Coll Cardiol 2011 Sep 13; 58:1211. Kleiman NS., J Am Coll Cardiol 2011 Sep 13; 58:1219.
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Left Main Coronary Artery Disease: Not Just for Bypass Anymore?
- April 4, 2011
- Howard C. Herrmann, MD
- Cardiology
In a randomized study, stent implantation compared well with CABG in most outcome measures.- Reviewing:
- Park S-J et al., N Engl J Med 2011 Apr 4;:
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Does a Gene Expression Test Help Identify Patients with Obstructive Coronary Artery Disease?
- November 3, 2010
- Joel M. Gore, MD
- Cardiology
Not yet.- Reviewing:
- Rosenberg S et al., Ann Intern Med 2010 Oct 5; 153:425. Arnett DK., Ann Intern Med 2010 Oct 5; 153:473.
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Ten-Year Findings from a Randomized Comparison of Coronary Artery Disease Therapies
- October 27, 2010
- Howard C. Herrmann, MD
- Cardiology
Compared with medical therapy, revascularization improved some long-term outcomes in patients with stable multivessel disease.
CME Exam- Reviewing:
- Hueb W et al., Circulation 2010 Sep 7; 122:949. Williams DO et al., Circulation 2010 Sep 7; 122:943.
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The 9p21 Genotype and Risk for Cardiovascular Disease
- October 13, 2010
- JoAnne M. Foody, MD
- Cardiology
Dosage of an at-risk variant appears to increase the risk for severe coronary artery disease, but the clinical implications of the genotype remain unclear.- Reviewing:
- Dandona S et al., J Am Coll Cardiol 2010 Aug 3; 56:479. Anderson JL and Horne BD., J Am Coll Cardiol 2010 Aug 3; 56:487.
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The Role of Computed Tomographic Coronary Angiography in the Diagnosis of Coronary Artery Disease
- June 2, 2010
- Joel M. Gore, MD
- Cardiology
CTCA was more accurate than stress testing, but clinical probability of disease should also guide the choice of noninvasive test.- Reviewing:
- Weustink AC et al., Ann Intern Med 2010 May 18; 152:630.
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What Is the Best Approach to Lipid Management?
- January 27, 2010
- Joel M. Gore, MD
- Cardiology
In a simulation study, basing statin treatment on overall cardiovascular risk produced better outcomes than basing treatment on target LDL levels.- Reviewing:
- Hayward RA et al., Ann Intern Med 2010 Jan 19; 152:69.
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Prognostic Value of a Highly Sensitive Troponin Assay in Patients with Stable Coronary Artery Disease
- December 9, 2009
- Harlan M. Krumholz, MD, SM
- Cardiology
Positive findings below conventional thresholds correlate with poor outcomes, but the importance of the test depends on the patient's overall risk profile.- Reviewing:
- Omland T et al. for the PEACE Investigators., N Engl J Med 2009 Nov 25;:
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CADENCE: A Snapshot of Angina in Primary Care Practice
- October 14, 2009
- Frederick A. Masoudi, MD, MSPH
- Cardiology
Symptom control in patients with CAD merits more attention.
CME Exam- Reviewing:
- Beltrame JF et al., Arch Intern Med 2009 Sep 14; 169:1491.
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Treating Diabetes and Coronary Artery Disease Free
- June 10, 2009
- Harlan M. Krumholz, MD, SM
- Cardiology
Prompt revascularization or initial medical therapy? Insulin sensitization or provision? From the BARI 2D trial, no strategy emerged a clear winner.
CME Exam- Reviewing:
- Frye RL et al. for the BARI 2D Study Group., N Engl J Med 2009 Jun 11; 360:2503. Boden WE and Taggart DP., N Engl J Med 2009 Jun 11; 360:2570.
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Women and Nonobstructive Coronary Artery Disease
- June 10, 2009
- Frederick A. Masoudi, MD, MSPH
- Cardiology
More evidence that the presence of ischemic symptoms without underlying obstructive arteriostenosis warrants heightened vigilance, if not intervention- Reviewing:
- Gulati M et al., Arch Intern Med 2009 May 11; 169:843.
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Which Revascularization Strategy Is Best for Severe Coronary Artery Lesions? Free
- February 18, 2009
- Howard C. Herrmann, MD
- Cardiology
Results of the SYNTAX trial failed to show that PCI is noninferior to CABG in patients with 3-vessel or left main disease.- Reviewing:
- Serruys PW et al for the SYNTAX Investigators., N Engl J Med 2009 Feb 18;: Lange RA and Hillis LD., N Engl J Med 2009 Feb 18;:
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Revascularization of Unprotected Left Main Lesions in Octogenarians
- January 14, 2009
- Howard C. Herrmann, MD
- Cardiology
Two-year results of a case-series study suggest that PCI might be a viable alternative to CABG, but only in carefully selected patients.- Reviewing:
- Rodés-Cabau J et al., Circulation 2008 Dec 2; 118:2374. Shemin RJ., Circulation 2008 Dec 2; 118:2326.
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A One-Two Punch for Coronary Risk in Patients with Diabetes
- November 26, 2008
- JoAnne M. Foody, MD
- Cardiology
Findings from a case–control and independent-cohort study suggest that genotype and poor glycemic control interact to predict CAD in diabetic patients.- Reviewing:
- Doria A et al., JAMA 2008 Nov 26; 300:2389.
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Meta-Analysis of Percutaneous Coronary Intervention in Stable Angina — A Contrast with COURAGE
- October 8, 2008
- Howard C. Herrmann, MD
- Cardiology
In pooled results from 17 randomized trials, PCI was associated with a survival advantage compared with medical therapy.
CME Exam- Reviewing:
- Schömig A et al., J Am Coll Cardiol 2008 Sep 9; 52:894. O’Rourke RA., J Am Coll Cardiol 2008 Sep 9; 52:905.
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Slowing Heart Rate with Ivabradine: Good, But Not Good Enough
- September 24, 2008
- Beat J. Meyer, MD
- Cardiology
In patients with CAD and LV dysfunction, If-channel blockage reduced ischemia-related symptoms but had no effect on mortality.- Reviewing:
- Fox K et al. on behalf of the BEAUTIFUL Investigators., Lancet 2008 Sep 6; 372:807. Fox K et al. on behalf of the BEAUTIFUL Investigators., Lancet 2008 Sep 6; 372:817.
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Routine Stress Testing for Patients with Stable Coronary Artery Disease?
- August 6, 2008
- Frederick A. Masoudi, MD, MSPH
- Cardiology
In a prospective study, inducible ischemia predicted adverse events better than angina symptoms did, but the evidence does not yet support a change in clinical practice.- Reviewing:
- Gehi AK et al., Arch Intern Med 2008 Jul 14; 168:1423.
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Erectile Dysfunction: A New Risk Factor for Heart Disease
- June 25, 2008
- Howard C. Herrmann, MD
- Cardiology
Results of two new studies make a strong case for including ED in cardiovascular risk assessment.- Reviewing:
- Gazzaruso C et al., J Am Coll Cardiol 2008 May 27; 51:2040. Ma RC et al., J Am Coll Cardiol 2008 May 27; 51:2045. Kloner RA., J Am Coll Cardiol 2008 May 27; 51:2051.
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