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Search for Heart Failure in Cardiology
Physician-authored summaries on the latest research on heart failure, editorials on heart failure, and perspectives on heart failure - drawn from the top medical journals.
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You searched for: heart failure in Cardiology
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Warfarin Ineffective for HF Without Atrial Fibrillation Free
In the WARCEF trial, reduced stroke rates were offset by increased bleeding.- Reviewing:
- Homma S et al., N Engl J Med 2012 May 2;:
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Autologous BMC Therapy for Heart Failure Disappoints in Phase II Trial
- April 18, 2012
- Frederick A. Masoudi, MD, MSPH, FACC, FAHA
- Cardiology
Transendocardial cell administration fails to improve left ventricular systolic function, maximal oxygen consumption, or defect size.- Reviewing:
- Perin EC et al., JAMA 2012 Mar 24;:
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Is Losartan as Good as Candesartan for HF? Free
- April 11, 2012
- Frederick A. Masoudi, MD, MSPH, FACC, FAHA
- Cardiology
A registry study suggests that it is, although the data contain many gaps.- Reviewing:
- Svanström H et al., JAMA 2012 Apr 11; 307:1506.
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Heart Failure in Patients with Infective Endocarditis: Surgery or No Surgery?
- December 7, 2011
- Harlan M. Krumholz, MD, SM
- Cardiology
A case series supports guideline recommendations for surgical treatment in patients with infective endocarditis and HF, although unmeasured confounders were probably in play.- Reviewing:
- Kiefer T et al., JAMA Nov 23/30; 306:2239.
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Can an Implantable Device Give Early Warning of Congestive Heart Failure?
- November 30, 2011
- Frederick A. Masoudi, MD, MSPH, FACC, FAHA
- Cardiology
An audible alert to patients when intrathoracic impedance crossed a defined threshold not only failed to improve outcomes, it increased the rate of HF hospitalization.
CME Exam- Reviewing:
- van Veldhuisen DJ et al., Circulation 2011 Oct 18; 124:1719. Udelson JETMI., Circulation 2011 Oct 18; 124:1697.
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Improvement in U.S. Heart Failure Outcomes, 1998–2008
- November 9, 2011
- Frederick A. Masoudi, MD, MSPH, FACC, FAHA
- Cardiology
Hospitalizations declined by 30%, and 1-year mortality declined by 7%.- Reviewing:
- Chen J et al., JAMA 2011 Oct 19; 306:1669.
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Delays in Treatment for STEMI Increase Risk for Heart Failure
- October 5, 2011
- Joel M. Gore, MD
- Cardiology
Findings from a population-based observational study suggest that reducing time from EMS call to PCI could improve morbidity as well as mortality.- Reviewing:
- Terkelsen CJ et al., Ann Intern Med 2011 Sep 20; 155:361.
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Omecamtiv Shows Early Promise for Heart Failure
- September 21, 2011
- Frederick A. Masoudi, MD, MSPH, FACC, FAHA
- Cardiology
In phase I and II trials, a cardiac myosin activator safely improved systolic function without increasing myocardial oxygen consumption.- Reviewing:
- Teerlink JR et al., Lancet 2011 Aug 20; 378:667. Cleland JGF et al., Lancet 2011 Aug 20; 378:676.
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Worsening Diastolic Function Predicts Heart Failure
- August 31, 2011
- Frederick A. Masoudi, MD, MSPH, FACC, FAHA
- Cardiology
Progression of diastolic dysfunction is an independent risk factor that warrants vigilance but not — at this point — screening or intervention.- Reviewing:
- Kane GC et al., JAMA 2011 Aug 24/31; 306:856.
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Stem Cell Infusion to Reverse Left Ventricular Remodeling: Encouraging Findings
- July 13, 2011
- Howard C. Herrmann, MD
- Cardiology
Bone marrow mononuclear cells transplanted during coronary artery bypass grafting significantly improved functional measures in patients with heart failure.- Reviewing:
- Hu S et al., J Am Coll Cardiol 2011 Jun 14; 57:2409.
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ASCEND-HF: Nesiritide Does Not Benefit Patients with Acute Heart Failure
- July 6, 2011
- Harlan M. Krumholz, MD, SM
- Cardiology
Rapid approval of the drug for early symptom relief has proven to be unjustified.
CME Exam- Reviewing:
- O'Connor CM et al., N Engl J Med 2011 Jul 7; 365:32.
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Copeptin Levels Predict Mortality in Patients with Heart Failure Symptoms
Independently and combined with N-terminal proBNP, a new biomarker was significantly associated with mortality risk in a primary-care cohort.- Reviewing:
- Alehagen U et al., JAMA 2011 May 25; 305:2088.
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Elderly Patients Continue to Be Excluded from Heart Failure Trials
Although HF is principally a disease of advancing age, the results of many clinical trials may not be generalizable to most elderly patients.- Reviewing:
- Cherubini A et al., Arch Intern Med 2011 Mar 28; 171:550. Gurwitz JH and Goldberg RJ., Arch Intern Med 2011 Mar 28; 171:557.
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HIV Independently Associated with Heart Failure Risk
- May 4, 2011
- JoAnne M. Foody, MD
- Cardiology
Observational data suggest that heightened vigilance and aggressive risk-factor management are warranted to prevent HF in HIV-infected individuals.- Reviewing:
- Butt AA et al., Arch Intern Med 2011 Apr 25; 171:737.
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Cardiac Troponin T: A New Tool in the Risk Prediction Kit
- April 27, 2011
- JoAnne M. Foody, MD
- Cardiology
A highly sensitive test may prove valuable in risk stratification of some individuals, but its role in treatment decisions remains undefined.- Reviewing:
- Saunders JT et al., Circulation 2011 Apr 5; 123:1367.
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The Changing Face of Heart Failure
- March 30, 2011
- Joel M. Gore, MD
- Cardiology
Patients living with HF are older, have more comorbidities, and take more medications than in the past.
CME Exam- Reviewing:
- Wong CY et al., Am J Med 2011 Feb; 124:136.
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Wireless Monitoring of Pulmonary Artery Pressure in Patients with Heart Failure
- March 9, 2011
- Harlan M. Krumholz, MD, SM
- Cardiology
An implantable sensor reduced the rate of hospitalization for HF, but the difference in out-of-hospital time was slight.- Reviewing:
- Abraham WT et al. for the CHAMPION Trial Study Group., Lancet 2011 Feb 19; 377:658.
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Diuretic Therapy for Acute Decompensated Heart Failure: Putting Practice to the Test Free
- March 2, 2011
- Harlan M. Krumholz, MD, SM
- Cardiology
Continuous infusion or bolus? Low or high dose? A comparative effectiveness trial provides needed data.- Reviewing:
- Felker GM et al for the NHLBI Heart Failure Clinical Research Network., N Engl J Med 2011 Mar 3; 364:797. Fonarow GC., N Engl J Med 2011 Mar 3; 364:877.
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Hospital Care for Congestive Heart Failure: Volume, Outcomes, and Cost
- February 9, 2011
- Joel M. Gore, MD
- Cardiology
In a retrospective study, a higher volume of patients with CHF was associated with better outcomes, but at a higher cost.
CME Exam- Reviewing:
- Joynt KE et al., Ann Intern Med 2011 Jan 18; 154:94.
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Candesartan vs. Losartan for Heart Failure Free
- January 19, 2011
- Harlan M. Krumholz, MD, SM
- Cardiology
Disturbing findings from a registry study call into question the class effects of angiotensin-receptor blockers.- Reviewing:
- Eklind-Cervenka M et al., JAMA 2011 Jan 12; 305:175.
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