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You searched for: statins in Cardiology
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Statins May Prevent Blocked Veins as Well as Blocked Arteries
- September 14, 2011
- Joel M. Gore, MD
- Cardiology
Atherosclerosis patients who received statins or antiplatelets had a lower incidence of VTE than those who did not, and the statin effect appeared to be dose-related.- Reviewing:
- Khemasuwan D et al., Am J Med 2011 Sep; 124:852.
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High-Dose Statins Before Percutaneous Coronary Intervention
- January 13, 2010
- Howard C. Herrmann, MD
- Cardiology
In statin-naive patients, a single loading dose of atorvastatin within 24 hours before PCI significantly reduced the rate of periprocedural MI.- Reviewing:
- Briguori C et al., J Am Coll Cardiol 2009 Dec 1; 54:2157. Tsimikas S., J Am Coll Cardiol 2009 Dec 1; 54:2164.
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Statins for Primary Prevention: Homing in on Effectiveness
- August 5, 2009
- Harlan M. Krumholz, MD, SM
- Cardiology
A new meta-analysis bolsters the case for benefit.- Reviewing:
- Brugts JJ et al., BMJ 2009 Jun 30; 338:b2376.
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Do Statins Prevent Cardiovascular Events in Hemodialysis Patients?
- March 30, 2009
- Harlan M. Krumholz, MD, SM
- Cardiology
Not according to findings from this randomized, controlled trial- Reviewing:
- Fellström BC et al., N Engl J Med 2009 Apr 2; 360:1395. Strippoli GFM and Craig JC., N Engl J Med 2009 Apr 2; 360:1455.
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Statins and Cognitive Impairment Free
- July 28, 2008
- Joel M. Gore, MD
- Cardiology
Findings from a prospective observational study support the thesis that statin use may protect against the eventual development of dementia.- Reviewing:
- Cramer C et al., Neurology 2008 Jul 29; 71:344.
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Do Statins Decrease Risk for Cancer?
- May 21, 2008
- Joel M. Gore, MD
- Cardiology
A multivariate analysis of observational data suggests that some of them might.- Reviewing:
- Karp I et al., Am J Med 2008 Apr; 121:302.
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Can Statins Benefit Elderly Patients with Ischemic Heart Failure? Free
- November 5, 2007
- Frederick A. Masoudi, MD, MSPH
- Cardiology
In a randomized trial, rosuvastatin was associated with a decrease in hospitalizations for cardiovascular events but no reduction in mortality.- Reviewing:
- Kjekshus J et al. for the CORONA group., N Engl J Med 2007 Nov 5;: Masoudi FA., N Engl J Med 2007 Nov 5;:
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Coenzyme Q10 for Relief of Muscle Ache in Patients Treated with Statins
- June 6, 2007
- Joel M. Gore, MD
- Cardiology
In a small study, supplements conferred a considerable benefit.- Reviewing:
- Caso G et al., Am J Cardiol 2007 May 15; 99:1409-12.
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Cost-Effectiveness of Primary-Prevention Therapy with Aspirin plus Statins
- April 6, 2006
- Joel M. Gore, MD
- Cardiology
For a healthy middle-aged man, the cost-effectiveness of combination therapy depends on his 10-year Framingham risk for cardiovascular events.- Reviewing:
- Pignone M et al., Ann Intern Med 2006 Mar 7; 144:326-36.
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Are Statins Beneficial After MI in Elders?
- March 30, 2006
- Allan S. Brett, MD
- Cardiology
These findings raise questions about the effectiveness of statins in patients age 80 or older.- Reviewing:
- Foody JM et al., J Am Geriatr Soc 2006 Mar; 54:421-30.
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Statins Do Not Affect Cancer Risk
- March 9, 2006
- JoAnne M. Foody, MD
- Cardiology
A meta-analysis of randomized controlled trials showed no effect on any type of cancer by any type of statin.- Reviewing:
- Dale KM et al., JAMA 2006 Jan 4; 295:74-80.
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Statins Might Prevent Sepsis in Older Patients with Atherosclerosis
- March 9, 2006
- Bruce Soloway, MD
- Cardiology
A population-based analysis revealed significantly lower rates of sepsis with statin use; randomized trials would be required to determine whether statins might be used specifically to prevent sepsis.- Reviewing:
- Hackam DG et al., Lancet 2006 Feb 4; 367:413-8.
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Statins for Nonischemic HF?
- February 23, 2006
- Frederick A. Masoudi, MD, MSPH
- Cardiology
Two randomized trials tested atorvastatin in patients with heart failure not due to coronary disease.- Reviewing:
- Sola S et al., J Am Coll Cardiol 2006 Jan 17; 47:332-7. Bleske BE et al., J Am Coll Cardiol 2006 Jan 17; 47:338-41. Ramasubbu K and Mann DL., J Am Coll Cardiol 2006 Jan 17; 47:342-4.
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Statins: Vascular Benefits Without Nonvascular Risk
- November 18, 2005
- JoAnne M. Foody, MD
- Cardiology
Evidence comes from a meta-analysis of 14 randomized, controlled trials of statins.- Reviewing:
- Cholesterol Treatment Trialists' (CTT) Collaborators., Lancet 2005 Oct 8; 366:1267-78.
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Statins Do Not Slow Calcific Aortic Stenosis
- July 15, 2005
- Harlan M. Krumholz, MD, SM
- Cardiology
Calcific aortic stenosis (AS) is a progressive form of valvular heart disease for which no preventive therapies exist. Like atherosclerosis, calcific AS is mediated by . . .- Reviewing:
- Cowell SJ et al. for the Scottish Aortic Stenosis and Lipid Lowering Trial, Impact on Regression (SALTIRE) Investigators., N Engl J Med 2005 Jun 9; 352:2389-97. Rosenhek R., N Engl J Med 2005 Jun 9; 352:2441-3.
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Do Statins Reduce Risk for Colorectal Cancer?
- July 1, 2005
- Harlan M. Krumholz, MD, SM
- Cardiology
Statins are best known for preventing heart disease. Interestingly, in vitro studies have shown that HMG-CoA reductase, the enzyme inhibited by statins, is overexpressed in . . .- Reviewing:
- Poynter JN et al., N Engl J Med 2005 May 26; 352:2184-92. Hawk E and Viner JL., N Engl J Med 2005 May 26; 352:2238-9.
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Statins and Low Cholesterol May Be Bad News for Human Embryos and Fetuses
- April 15, 2005
- Judith G. Hall, OC, MD
- Cardiology
The FDA currently classifies statins as pregnancy category X (contraindicated) drugs, based on animal studies and the importance of cholesterol biosynthesis in fetal development. In . . .- Reviewing:
- Edison RJ and Muenke M., Am J Med Genet 2004 Dec 15; 131A:287-98.
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Do Statins Reduce Risk for Dementia?
- March 18, 2005
- Allan S. Brett, MD
- Cardiology
Several cross-sectional and case-control studies have suggested that statins protect against development of dementia. However, prospective studies are better suited to examine this relation.- Reviewing:
- Zandi PP et al., Arch Gen Psychiatry 2005 Feb; 62:217-24. Li G et al., Neurology 2004 Nov 9; 63:1624-8.
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Discussion on CardioExchange: Uncertainty Over the Clinical Importance of the Diabetes Risk of Diuretics and Statins Free
- March 28, 2012
- The Editors
- Cardiology
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Do Statins Slow Progression of Rheumatic Mitral Stenosis?
- July 14, 2010
- Howard C. Herrmann, MD
- Cardiology
Findings from a retrospective study suggest that they do.- Reviewing:
- Antonini-Canterin F et al., Circulation 2010 May 18; 121:2130.
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