Biomarker Changes Associated with Physiologic Responses to Air Pollution
SUMMARY AND COMMENT
A study in healthy individuals during the Beijing Olympics points to a prothrombotic mechanism.
Reviewing:
Rich DQ et al., JAMA 2012 May 16; 307:2068
Dominici F and Mittleman MA., JAMA 2012 May 16; 307:2100
Among Older Patients with AF, Stroke Risk Is Higher in Women Than in Men
SUMMARY AND COMMENT
In a population-based cohort, the increase was independent of comorbidities, baseline risk score, or warfarin use.
Reviewing:
Avgil Tsadok M et al., JAMA 2012 May 9; 307:1952
Discussion on CardioExchange: A "Brilinta" Theory on Why Ticagrelor Doesn't Work as Well in the U.S.
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Warfarin Ineffective for HF Without Atrial Fibrillation
SUMMARY AND COMMENT
In the WARCEF trial, reduced stroke rates were offset by increased bleeding.
Reviewing:
Homma S et al., N Engl J Med 2012 May 2
Hospital Strategies for Decreasing AMI Mortality
SUMMARY AND COMMENT
Five specific organizational practices significantly associated with lower risk-standardized mortality rates
Reviewing:
Bradley EH et al., Ann Intern Med 2012 May 1; 156:618
Long-Term Safety of Biodegradable Coronary Stents
SUMMARY AND COMMENT
Excellent 10-year results in the first cohort of poly-l -lactic–acid stent recipients allay one concern, but the clinical role of this device remains unclear.
Reviewing:
Nishio S et al., Circulation 2012 Apr 16
Waksman R., Circulation 2012 Apr 16
A Snapshot of Real-World TAVR Results
SUMMARY AND COMMENT
In a French registry study, outcomes were similar to those in the PARTNER trial.
Reviewing:
Gilard M et al., N Engl J Med 2012 May 3; 366:1705
Discussion on CardioExchange: Patent Foramen Ovale — Are the Choices Patently Obvious?
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Discussion on CardioExchange: Frailty Evaluation and High-Risk Interventions
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How Meaningful Are Troponin Elevations After PCI?
SUMMARY AND COMMENT
Registry findings raise questions about the current threshold for MI.
Reviewing:
Novack V et al., Arch Intern Med 2012 Mar 26; 172:502
Alpert JS and Jaffe AS., Arch Intern Med 2012 Mar 26; 172:508