Should Coronary Angiography Be Routine Before Vascular Surgery?
SUMMARY AND COMMENT
Findings from a small randomized trial show long-term benefits.
Reviewing:
Monaco M et al., J Am Coll Cardiol 2009 Sep 8; 54:989
Landesberg G and Mosseri M., J Am Coll Cardiol 2009 Sep 8; 54:997
Implantable Cardioverter-Defibrillators After MI: Keep the Brakes On
SUMMARY AND COMMENT
October 7, 2009
Mark S. Link, MD
Results of a randomized trial confirm that early ICD implantation fails to improve survival.
Reviewing:
Steinbeck G et al., N Engl J Med 2009 Oct 8; 361:1427
Garber AM and Hlatky MA., N Engl J Med 2009 Oct 8; 361:1498
A New Factor Xa Inhibitor Prepares for Its Close-Up
SUMMARY AND COMMENT
Otamixaban shows promise in patients with ACS, but do we really need another intravenous anticoagulant?
Reviewing:
Sabatine MS et al., Lancet 2009 Sep 5; 374:787
Eikelboom JW and Weitz JI., Lancet 2009 Sep 5; 374:762
Resistant Hypertension: Is There a Role for a New Drug?
SUMMARY AND COMMENT
October 7, 2009
Joel M. Gore, MD
An endothelin antagonist performed well in a randomized trial, but much research remains to be done.
Reviewing:
Weber MA et al., Lancet 2009 Sep 14
Williams B., Lancet 2009 Sep 14
Coronary Artery Bypass Grafting After Percutaneous Coronary Intervention
SUMMARY AND COMMENT
Findings from a large observational study support the safety of a "PCI first" strategy in many patients.
Reviewing:
Yap C-H et al., JACC Cardiovasc Interv 2009 Aug; 2:758
Mack M., JACC Cardiovasc Interv 2009 Aug; 2:765
Elevated Troponin After Coronary Bypass Surgery: What Does It Mean?
SUMMARY AND COMMENT
September 30, 2009
Joel M. Gore, MD
Observational findings suggest that very high TnT levels predict adverse outcomes.
Reviewing:
Mohammed AA et al., Circulation 2009 Sep 8; 120:843
High Blood Pressure and Dementia: New Data
SUMMARY AND COMMENT
September 23, 2009
JoAnne M. Foody, MD
In a large observational study, increased DBP correlated with increased odds of dementia.
CME
Reviewing:
Tsivgoulis G et al., Neurology 2009 Aug 25; 73:589
Prasugrel and Glycoprotein IIb/IIIa Inhibition in Percutaneous Coronary Intervention
SUMMARY AND COMMENT
In an observational analysis of TRITON-TIMI 38 data, prasugrel outperformed clopidogrel in patients with ACS, whether or not they received GP IIb/IIIa inhibitors.
Reviewing:
O'Donoghue M et al., J Am Coll Cardiol 2009 Aug 18; 54:678
Treating Resistant Hypertension: Cut Out the Salt
SUMMARY AND COMMENT
September 23, 2009
Joel M. Gore, MD
In a small randomized crossover study, a low-salt diet had dramatic effects on blood pressure.
CME
Reviewing:
Pimenta E et al., Hypertension 2009 Sep; 54:475
Warfarin for Stroke Prevention in Patients with Atrial Fibrillation
SUMMARY AND COMMENT
September 16, 2009
Joel M. Gore, MD
Results of a large observational study provide current data for accurate risk-benefit estimation.
CME
Reviewing:
Singer DE et al., Ann Intern Med 2009 Sep 1; 151:297
