Intervention for Non–ST-Segment-Elevation Acute Coronary Syndromes: What Difference Does a Day Make?
SUMMARY AND COMMENT
September 16, 2009
Beat J. Meyer, MD
Interventions performed immediately or deferred to the next working day resulted in similar outcomes.
Reviewing:
Montalescot G et al., JAMA 2009 Sep 2; 302:947
Acute MI in the U.S.: Risk-Standardized Mortality Rates, 1995 to 2006
SUMMARY AND COMMENT
September 9, 2009
Joel M. Gore, MD
The odds of dying within 30 days after hospital discharge have declined significantly.
Reviewing:
Krumholz HM et al., JAMA 2009 Aug 19; 302:767
A Genotype Associated with Diminished Response to Clopidogrel
SUMMARY AND COMMENT
A genomewide association study nudges genetic testing closer to clinical practice.
Reviewing:
Shuldiner AR et al., JAMA 2009 Aug 26; 302:849
Bhatt DL., JAMA 2009 Aug 26; 302:896
Correction: An Alternative to Warfarin in Patients with Atrial Fibrillation?
CORRECTION
September 9, 2009
The Editors
A correction to a summary published September 1, 2009
Magnetic Resonance Imaging in Patients with Implantable Cardioverter-Defibrillators: The Walls Are Crumbling
SUMMARY AND COMMENT
September 2, 2009
Mark S. Link, MD
More and more evidence is accumulating that patients with ICDs can safely undergo MRI.
Reviewing:
Naehle CP et al., J Am Coll Cardiol 2009 Aug 4; 54:549
Roguin A., J Am Coll Cardiol 2009 Aug 4; 54:556
Idiopathic Ventricular Fibrillation Is Becoming Less Idiopathic
SUMMARY AND COMMENT
September 2, 2009
Mark S. Link, MD
More than 50% of individuals with idiopathic VF can ultimately receive diagnoses of a cardiac disease after a thorough investigation.
Reviewing:
Krahn AD et al., Circulation 2009 Jul 28; 120:278
Refining Antiplatelet Treatment in Patients with Acute Coronary Syndromes
SUMMARY AND COMMENT
September 2, 2009
Beat J. Meyer, MD
In a randomized trial, oral ticagrelor outperformed clopidogrel.
Reviewing:
Wallentin L et al. for the PLATO Investigators., N Engl J Med 2009 Sep 10; 361:1045
Cardiac Resynchronization Therapy to Prevent Heart Failure: Gathering Momentum
SUMMARY AND COMMENT
September 1, 2009
Mark S. Link, MD
MADIT-CRT findings demonstrate a benefit of resynchronization in patients with NYHA class I or II heart failure.
Reviewing:
Moss AJ et al., N Engl J Med 2009 Sep 1
Can Thienopyridines and Proton-Pump Inhibitors Peacefully Coexist?
SUMMARY AND COMMENT
An observational analysis of trial data confirms the functional interaction but provides no evidence of adverse clinical effects.
CME
Reviewing:
O'Donoghue ML et al., Lancet 2009 Sep 1
An Alternative to Warfarin in Patients with Atrial Fibrillation?
SUMMARY AND COMMENT
Compared with warfarin, low-dose dabigatran performed better with regard to safety but not efficacy, and high-dose dabigatran performed better with regard to efficacy but not safety.
Reviewing:
Connolly SJ et al. for the RE-LY Steering Committee and Investigators., N Engl J Med 2009 Aug 30
