An Herbal Option for Statin-Intolerant Patients?
SUMMARY AND COMMENT
A supplement of red yeast rice outperforms placebo in a small randomized trial.
Reviewing:
Becker DJ et al., Ann Intern Med 2009 Jun 16; 150:830
Phillips PS., Ann Intern Med 2009 Jun 16; 150:885
More Burn, Higher Return
SUMMARY AND COMMENT
An increase in the prescribed energy expenditure of a cardiac rehabilitation program improved cardiac risk profiles.
Reviewing:
Ades PA et al., Circulation 2009 May 11
Can D-Dimer Levels Help Rule Out Acute Aortic Dissection?
SUMMARY AND COMMENT
In a case-control analysis, the negative likelihood ratio associated with levels <500 ng/mL was comparable to that considered sufficient to rule out pulmonary embolism.
Reviewing:
Suzuki T et al. for the IRAD-Bio Investigators., Circulation 2009 May 26; 119:2702
Long-Term Follow-Up After Sirolimus-Eluting Stent Implantation
SUMMARY AND COMMENT
Five-year results of a landmark trial confirm the benefits and safety of on-label use of SES.
Reviewing:
Weisz G et al., J Am Coll Cardiol 2009 Apr 28; 53:1488
Treating Diabetes and Coronary Artery Disease
SUMMARY AND COMMENT
Prompt revascularization or initial medical therapy? Insulin sensitization or provision? From the BARI 2D trial, no strategy emerged a clear winner.
Reviewing:
Frye RL et al. for the BARI 2D Study Group., N Engl J Med 2009 Jun 11; 360:2503
Boden WE and Taggart DP., N Engl J Med 2009 Jun 11; 360:2570
Duration of Anticoagulation Therapy After Deep Venous Thrombosis
SUMMARY AND COMMENT
In a randomized trial, the use of ultrasonography to guide treatment continuation reduced thrombosis recurrence.
Reviewing:
Prandoni P et al., Ann Intern Med 2009 May 5; 150:577
Women and Nonobstructive Coronary Artery Disease
SUMMARY AND COMMENT
More evidence that the presence of ischemic symptoms without underlying obstructive arteriostenosis warrants heightened vigilance, if not intervention
Reviewing:
Gulati M et al., Arch Intern Med 2009 May 11; 169:843
Should Carotid Stenting Be Performed in Octogenarians?
SUMMARY AND COMMENT
Results of a case series suggest that the procedure can be safe and effective, but its net benefit in these patients remains to be determined.
Reviewing:
Chiam PTL et al., Circulation 2009 May 5; 119:2343
Belkin M and Bhatt DL., Circulation 2009 May 5; 119:2302
Reducing Radiation Exposure from Cardiac Computed Tomography
SUMMARY AND COMMENT
A coordinated quality-improvement initiative produced impressive results.
Reviewing:
Raff GL et al. for the Advanced Cardiovascular Imaging Consortium Co-Investigators., JAMA 2009 Jun 10; 301:2340
Someone to Watch Over Meds
SUMMARY AND COMMENT
In two studies, researchers explore novel strategies for reducing adverse drug events caused by medication errors.
Reviewing:
Murray MD et al., Arch Intern Med 2009 Apr 27; 169:757
Schnipper JL et al., Arch Intern Med 2009 Apr 27; 169:771