A Closer Look at Aspirin for Primary Prevention
SUMMARY AND COMMENT
A meta-analysis of individual patient data from six trials uncovers no clear benefit.
Reviewing:
Collins R et al. for the Antithrombotic Trialists’ (ATT) Collaboration., Lancet 2009 May 30; 373:1849
Algra A and Greving JP., Lancet 2009 May 30; 373:1821
Ablation for Atrial Fibrillation: Not Risk Free
SUMMARY AND COMMENT
The risk for death after AF ablation is 1 in 1000 patients or 1 in 1385 procedures.
CME
Reviewing:
Cappato R et al., J Am Coll Cardiol 2009 May 12; 53:1798
Belhassen B., J Am Coll Cardiol 2009 May 12; 53:1804
Which Drug-Eluting Stent Is Best for Left Main Lesions?
SUMMARY AND COMMENT
In a randomized trial, PES and SES produced similarly good results.
Reviewing:
Mehilli J et al., J Am Coll Cardiol 2009 May 12; 53:1760
Alfonso F., J Am Coll Cardiol 2009 May 12; 53:1769
Estradiol and Mortality in Men with Heart Failure
SUMMARY AND COMMENT
In an observational study, both high and low estradiol levels were associated with increased mortality.
Reviewing:
Jankowska EA et al., JAMA 2009 May 13; 301:1892
Where Should I Go for My Cardiac Surgery?
SUMMARY AND COMMENT
In an observational study, outcomes correlated better with adherence to six quality-of-care measures than with hospital or operator volume.
Reviewing:
Auerbach AD et al., Ann Intern Med 2009 May 19; 150:696
Bach PB., Ann Intern Med 2009 May 19; 150:729
Glycoprotein IIb/IIIa Inhibition After Clopidogrel Loading for Primary Percutaneous Coronary Intervention
SUMMARY AND COMMENT
In a randomized trial, abciximab showed no benefit in clopidogrel-treated STEMI patients.
Reviewing:
Mehilli J et al., Circulation 2009 Apr 14; 119:1933
We Are What We Eat
SUMMARY AND COMMENT
A MESA analysis reveals substantial differences among four ethnic groups in reaching adherence targets for eight components of the DASH diet.
Reviewing:
Gao SK et al., Arch Intern Med 2009 Apr 13; 169:702
Physical Activity Advice from Primary Care Physicians
SUMMARY AND COMMENT
In a randomized trial, systematically advising patients improved their activity levels.
Reviewing:
Grandes G et al., Arch Intern Med 2009 Apr 13; 169:694
Ventricular Tachycardia or Fibrillation and ST-Segment-Elevation MI: Does Percutaneous Coronary Intervention Improve Outcomes?
SUMMARY AND COMMENT
In the era of primary PCI for STEMI, VT/VF is still an ominous prognostic indicator.
Reviewing:
Mehta RH et al. for the APEX AMI Investigators., JAMA 2009 May 6; 301:1779
Early or Delayed Intervention for Acute Coronary Syndromes Without ST-Segment-Elevation?
SUMMARY AND COMMENT
In a randomized trial, only high-risk patients clearly benefited from invasive treatment within 24 hours.
Reviewing:
Mehta SR et al. for the TIMACS Investigators., N Engl J Med 2009 May 21; 360:2165