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Reader Remarks on:

The ACCORD and ADVANCE Trials: Implications for Patients with Type 2 Diabetes

How to achieve intense glycaemic control

Bassem Zarif Fouad, National Heart Institute, Egypt, 23 May 2009 5:10 AM EST

Competing interests: None declared

I think that different hypoglycaemic agents used to achieve intense blood glucose control, were sure having different effects on ( macro- vascular )CV risk . And the concept that intense blood glucose control had no or worst outcome on CV risk, is something too early and may be very deleterious . we should include in the data analysis the agent(S) used to achieve intense glucose control and other risk factors control status in a multivariate analysis to get the proper evaluation of the effect of intense glucose on Macro-vascular complications .

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